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DuPont has been using Dulux enamel in automotive coatings since 1926. Dulux actually owes its existence to a flaw in its more famous cousin, Duco. This nitrocellulose lacquer first brought color to automobiles when General Motors used it in 1923. It was thick and quick drying, which pleased carmakers, but frustrating for consumers who couldn't apply it like the oil-based paints they were used to. So DuPont researchers tried mixing synthetic alkyd resins with oil and found that the resulting enamel's drying time was slower than Duco but faster than that of traditional oil paint. Dulux alkyd resin, named in 1926, also had a pleasing high-gloss look. By the early 1930s it won over consumers under the label Dulux "Brush" Duco.

Dulux high-gloss enamels were also used widely in the 1930s on refrigerators and washing machines, outdoor signs, gasoline service stations and pumps, and railroad cars. Once tried as an undercoating for Duco auto paint, Dulux also found a niche as a low-cost alternative to Duco auto finishes. In 1954 some automobile manufacturers chose an improved Dulux alkyd enamel over Duco, and over DuPont's new water-based Lucite® acrylic lacquer. However, Lucite® soon pulled ahead in household sales, and after DuPont developed a new acrylic polymer in 1957, Lucite® also outshone Dulux in the appliance and industrial markets. DuPont sold its consumer paint business in 1983.

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